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. 2016 Jan 29;60(2):797–805. doi: 10.1128/AAC.00426-15

TABLE 1.

Inhibition of CL, CB, LmCPB2.8, and LmaCatB, antileishmanial activity against L. major promastigotes, and cytotoxicity by trans-aziridine-2,3-dicarboxylates 13b, 13e, and s1 to s38c

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a

Diastereomeric ratio (dr) = 1:0.59.

b

Diastereomeric ratio (dr) = 1:0.55.

c

Bn, benzyl ester; Et, ethyl ester; pBr-Bn, para-bromo-benzylester; NI, no inhibition; ND, not determined; NDp, not determined because of precipitation; J774.1, macrophage cell line; Nip, nipecotic acid; CB, cathepsin B; CL, cathepsin L.