TABLE 2.

Antileishmanial activities of trans-aziridine-2,3-dicarboxylates 13b, 13e, s9, s17, s24, and s25 and of standard inhibitors against L. major amastigotes

Compound	L. major IC50 (μM)
13b	2.2 ± 1.5
13e	2.7 ± 0.7
s9	2.3 ± 0.6
s17	1.6 ± 0.3
s24	2.2 ± 0.6
s25	2.0 ± 0.6
E-64d	39.8 ± 11.3
CLIK-148	>100
CA074ME	>100