Fig. 1.

Mesoglycan and Heparin induce AMPK activation in VSMC. Cells were treated with the indicated concentration of mesoglycan for 1 h (a) or for the indicated periods (b). Protein expression of p-LKB1, p-AMPK, and p-ACC were determined by western blot analysis. VSMCs were treated with the indicated concentration of heparin for 2 h (c) or for the indicated periods (d). Protein expression of p-LKB1, p-AMPK, and p-ACC were determined by western blot analysis. Representative results from three independent experiments were shown. *p <0.05 versus the control