Table 3. Factors influencing achievement of therapeutic trough concentrations of 10–20 mcg/mL.

Variable	P
Age	.0160
Age ≥ 45 years	.0073
SCr	.3979
CrCl <100 mL/min	.0170
ICU status	.0850
Total body weight	.1350
Percentage above ideal body weight	.0567
Comorbidities ≥1	.7395
Diabetes	.9772
Other nephrotoxic therapy	.6034

Note: CrCl = creatinine clearance; ICU = intensive care unit; SCr = serum creatinine.