Table 3. Results for Hepcidin-25 among GH-deficient patients studied prior to and during one years of replacement with GH [25].
| GH-deficiency, Median, (lower and upper quartile) | GH- treated, Median, (lower and upper quartile) | P value | |
|---|---|---|---|
| IGF-1(ug/L) | 86.5 (66–112) | 195.5 (144–225) | < 0.01 |
| Iron (uM/L) | 16.5 (14–20) | 20.5 (18–22) | ns |
| TIBC (%) | 0.27 (0,25–0.37) | 0.32 (0.27–0.39) | ns |
| Transferrin (g/L) | 2.28 (2.26–2.47) | 2.4 (2,21–2.66) | ns |
| CRP (mg/L) | 3.15 (1.4–3.9) | 1.7 (1.2–2.6) | <0.01 |
| Ferritin (ug/L) | 65 (45–215) | 47 (40–160) | ns |
| Hepcidin-25 (ng/mL) | 6.2 (4.04–15.25) | 13.15 (7.05–16.1) | ns |
Results for Hepcidin-25, CRP, ferritin, transferrin, TIBC and IGF-1 concentrations are expressed as median, (lower and upper quartile). Significance level was set at p < 0.05. For statistical calculation the Wilcoxon signed-rank test were used.