Table 5. Results for Hepcidin-25 before and after six month treatment of prolactinoma with dopamine agonist therapy [23].
| Untreated prolactinoma Median, (lower and upper quartile) | treated prolactinoma Median, (lower and upper quartile) | P value | |
|---|---|---|---|
| Prolactin (ug/L) | 1066.0±674.75 | 9.16±1.05 | <0.0001 |
| Iron (uM/L) | 21 (17–22) | 14.0 (11.0–18.0) | ns |
| TIBC (%) | 0.32 (0.25–0.38) | 0.21 (0.17–0.28) | ns |
| Transferrin (g/L) | 2.59 (2.3–3.08) | 2.52 (2.41–2.82) | ns |
| CRP (mg/L) | 1.0 (0.38–1.5) | 0.69 (0.29–1.20) | ns |
| Ferritin (ug/L) | 52.5 (32.5–79.5) | 36.0 (24.5–66.5) | ns |
| Hepcidin-25 (ng/mL) | 8.52 (4.8–20.95) | 4.31 (2.84–7.40) | ns |
Results for Hepcidin-25, CRP, ferritin, transferrin, TIBC and prolactine concentrations are expressed as median, (lower and upper quartile). Significance level was set at p < 0.05. For statistical calculation the Wilcoxon signed-rank test were used.