Table 2. Health-related quality of life (HR-QoL) domains in participants by BMI categories and MDD and/or anxiety disorders: deviation with standard error from the mean for normal weight participants.
No MDD/anxiety disorder (n = 79820) | Anxiety alone (n = 8838) | Major depression alone (n = 2004) | MDD/anxiety disorder (n = 9512) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Normal weight, mean (SD)a | Over-weight | Mild obesity | Moderate/ Severe obesity | Normal weight, mean (SD)a | Over-weight | Mild obesity | Moderate/ Severe obesity | Normal weight | Over-weight | Mild obesity | Moderate obesity | Normal weight, mean (SD)a | Over-weight | Mild obesity | Moderate/ Severe obesity | |
Physical function | 93.6 (11.2) | -2.7 (0.1) | -7.2 (0.2) | -13.7 (0.3) | 82.5 (24.8) | -3.8 (0.4) | -10.8 (0.6) | -18.3 (0.8) | 82.0 (19.3) | -5.2 (1.1) | -14.6 (1.4) | -21.4 (1.7) | 87.6 (15.9) | -3.8 (0.4) | -11.1 (0.6) | -19.4 (0.8) |
Role-physical | 89.7 (25.9) | -1.2 (0.2) | -5.3 (0.3) | -9.0 (0.5) | 77.2 (34.5) | -4.0 (0.9) | -11.4 (1.3) | -15.9 (1.8) | 58.0 (43.5) | -6.0 (2.3) | -12.1 (2.9) | -18.6 (3.5) | 73.9 (38.0) | -3.9 (0.9) | -11.5 (1.3) | -17.4(1.7) |
Role-emotional | 93.9 (20.2) | 0.2 (0.2) | -1.3 (0.2) | -2.5 (0.4) | 72.9 (38.9) | 2.0 (1.0) | -2.6 (1.4) | -9.1 (1.9) | 38.7 (42.9) | 0.2 (2.2) | -0.5 (2.8) | -2.6 (3.4) | 64.9 (42.2) | 2.0 (1.0) | -3.0 (1.4) | -9.4 (1.9) |
Social functioning | 89.9 (15.5) | 0.2 (0.1) | -1.4 (0.2) | -3.6 (0.3) | 64.5 (22.4) | 0.5 (0.6) | -2.7 (0.8) | -8.3 (1.2) | 51.1 (25.3) | 0.7 (1.3) | 0.3 (1.6) | -6.8 (2.0) | 69.7 (24.7) | 0.6 (0.6) | -2.7 (0.8) | -8.7 (1.1) |
Bodily pain | 86.9 (17.2) | -1.6 (0.1) | -4.9 (0.2) | -8.7 (0.4) | 69.5 (26.0) | -2.0 (0.5) | -7.0 (0.8) | -11.6 (1.0) | 68.2 (24.8) | -4.0 (1.3) | -8.3 (1.7) | -14.2 (2.0) | 76.5 (21.7) | -2.0 (0.5) | -6.9 (0.7) | -12.1 (1.0) |
Mental health | 81.1 (11.7) | 1.1 (0.1) | 0.7 (0.1) | -0.5 (0.2) | 58.2 (15.3) | 1.3 (0.4) | 0.3 (0.6) | -3.6 (0.8) | 48.2 (18.1) | 0.7 (0.9) | 1.0 (1.1) | -2.1 (1.4) | 63.2(17.9) | 1.3 (0.4) | 0.1 (0.6) | -3.8 (0.8) |
Vitality | 69.6 (15.4) | 0.2 (0.1) | -2.2 (0.2) | -5.4 (0.3) | 54.6 (15.5) | 0.1 (0.4) | -2.4 (0.6) | -7.1 (0.9) | 38.4 (17.1) | -0.3 (0.8) | -1.9 (1.1) | -5.1 (1.3) | 52.7 (18.9) | -0.2 (0.4) | -2.8 (0.6) | -7.4 (0.8) |
General health | 69.7 (11.6) | -0.6 (0.1) | -1.8 (0.1) | -4.5 (0.2) | 58.6 (12.1) | -1.3 (0.3) | -3.8 (0.5) | -7.2 (0.7) | 58.2 (15.7) | -2.2 (0.8) | -3.1 (1.0) | -8.1 (1.2) | 63.2 (14.3) | -1.2 (0.3) | -3.7 (0.5) | -7.5 (0.6) |
PCS | 52.4 (6.3) | -1.0 (0.1) | -2.8 (0.1) | -5.0 (0.1) | 49.6 (10.1) | -1.8 (0.2) | -4.5 (0.3) | -6.6. (0.4) | 49.9 (10.1) | -2.5 (0.6) | -5.6 (0.7) | -8.5 (0.8) | 51.1 (8.6) | -1.8 (0.2) | -4.5 (0.3) | -7.0 (0.4) |
MCS | 53.4 (6.8) | 0.7 (0.1) | 0.7 (0.1) | 0.6 (0.1) | 41.3 (11.1) | 1.3 (0.3) | 0.9 (0.4) | -1.0 (0.6) | 32.3 (12.0) | 1.2 (0.6) | 2.3 (0.8) | 1.2 (0.9) | 42.1 (12.4) | 1.3 (0.3) | 0.8 (0.4) | -1.0 (0.5) |
a Reference group
SD: standard deviation; MDD: major depressive disorder; HR-QoL: Health related quality of life; PCS: physical component summary score; MCS: Mental component summary score; Normal weight (BMI: 18.5–24.99kg/m2), overweight (BMI 25.0–29.99 kg/m2), mild obesity (BMI 30.0–34.99 kg/m2) and moderate/severe obesity (BMI ≥ 35.0 kg/m2); Bold figures reflect statistically significant deviations from the mean for normal weight participants (p<0.05).