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. 2016 Feb 11;11(2):e0148871. doi: 10.1371/journal.pone.0148871

Table 2. Health-related quality of life (HR-QoL) domains in participants by BMI categories and MDD and/or anxiety disorders: deviation with standard error from the mean for normal weight participants.

No MDD/anxiety disorder (n = 79820) Anxiety alone (n = 8838) Major depression alone (n = 2004) MDD/anxiety disorder (n = 9512)
Normal weight, mean (SD)a Over-weight Mild obesity Moderate/ Severe obesity Normal weight, mean (SD)a Over-weight Mild obesity Moderate/ Severe obesity Normal weight Over-weight Mild obesity Moderate obesity Normal weight, mean (SD)a Over-weight Mild obesity Moderate/ Severe obesity
Physical function 93.6 (11.2) -2.7 (0.1) -7.2 (0.2) -13.7 (0.3) 82.5 (24.8) -3.8 (0.4) -10.8 (0.6) -18.3 (0.8) 82.0 (19.3) -5.2 (1.1) -14.6 (1.4) -21.4 (1.7) 87.6 (15.9) -3.8 (0.4) -11.1 (0.6) -19.4 (0.8)
Role-physical 89.7 (25.9) -1.2 (0.2) -5.3 (0.3) -9.0 (0.5) 77.2 (34.5) -4.0 (0.9) -11.4 (1.3) -15.9 (1.8) 58.0 (43.5) -6.0 (2.3) -12.1 (2.9) -18.6 (3.5) 73.9 (38.0) -3.9 (0.9) -11.5 (1.3) -17.4(1.7)
Role-emotional 93.9 (20.2) 0.2 (0.2) -1.3 (0.2) -2.5 (0.4) 72.9 (38.9) 2.0 (1.0) -2.6 (1.4) -9.1 (1.9) 38.7 (42.9) 0.2 (2.2) -0.5 (2.8) -2.6 (3.4) 64.9 (42.2) 2.0 (1.0) -3.0 (1.4) -9.4 (1.9)
Social functioning 89.9 (15.5) 0.2 (0.1) -1.4 (0.2) -3.6 (0.3) 64.5 (22.4) 0.5 (0.6) -2.7 (0.8) -8.3 (1.2) 51.1 (25.3) 0.7 (1.3) 0.3 (1.6) -6.8 (2.0) 69.7 (24.7) 0.6 (0.6) -2.7 (0.8) -8.7 (1.1)
Bodily pain 86.9 (17.2) -1.6 (0.1) -4.9 (0.2) -8.7 (0.4) 69.5 (26.0) -2.0 (0.5) -7.0 (0.8) -11.6 (1.0) 68.2 (24.8) -4.0 (1.3) -8.3 (1.7) -14.2 (2.0) 76.5 (21.7) -2.0 (0.5) -6.9 (0.7) -12.1 (1.0)
Mental health 81.1 (11.7) 1.1 (0.1) 0.7 (0.1) -0.5 (0.2) 58.2 (15.3) 1.3 (0.4) 0.3 (0.6) -3.6 (0.8) 48.2 (18.1) 0.7 (0.9) 1.0 (1.1) -2.1 (1.4) 63.2(17.9) 1.3 (0.4) 0.1 (0.6) -3.8 (0.8)
Vitality 69.6 (15.4) 0.2 (0.1) -2.2 (0.2) -5.4 (0.3) 54.6 (15.5) 0.1 (0.4) -2.4 (0.6) -7.1 (0.9) 38.4 (17.1) -0.3 (0.8) -1.9 (1.1) -5.1 (1.3) 52.7 (18.9) -0.2 (0.4) -2.8 (0.6) -7.4 (0.8)
General health 69.7 (11.6) -0.6 (0.1) -1.8 (0.1) -4.5 (0.2) 58.6 (12.1) -1.3 (0.3) -3.8 (0.5) -7.2 (0.7) 58.2 (15.7) -2.2 (0.8) -3.1 (1.0) -8.1 (1.2) 63.2 (14.3) -1.2 (0.3) -3.7 (0.5) -7.5 (0.6)
PCS 52.4 (6.3) -1.0 (0.1) -2.8 (0.1) -5.0 (0.1) 49.6 (10.1) -1.8 (0.2) -4.5 (0.3) -6.6. (0.4) 49.9 (10.1) -2.5 (0.6) -5.6 (0.7) -8.5 (0.8) 51.1 (8.6) -1.8 (0.2) -4.5 (0.3) -7.0 (0.4)
MCS 53.4 (6.8) 0.7 (0.1) 0.7 (0.1) 0.6 (0.1) 41.3 (11.1) 1.3 (0.3) 0.9 (0.4) -1.0 (0.6) 32.3 (12.0) 1.2 (0.6) 2.3 (0.8) 1.2 (0.9) 42.1 (12.4) 1.3 (0.3) 0.8 (0.4) -1.0 (0.5)

a Reference group

SD: standard deviation; MDD: major depressive disorder; HR-QoL: Health related quality of life; PCS: physical component summary score; MCS: Mental component summary score; Normal weight (BMI: 18.5–24.99kg/m2), overweight (BMI 25.0–29.99 kg/m2), mild obesity (BMI 30.0–34.99 kg/m2) and moderate/severe obesity (BMI ≥ 35.0 kg/m2); Bold figures reflect statistically significant deviations from the mean for normal weight participants (p<0.05).