Table 5. Predictors of ypT0 in the breast after completion of NCT.
Parameters | Odds ratio | 95% CI | P-value |
---|---|---|---|
Breast cancer subtype | 0.098 | ||
HRs+/HER2- | Ref | ||
HRs+/HER2+ | 0.70 | 0.16–3.00 | 0.633 |
HRs-/HER2+ | 0.97 | 0.26–3.54 | 0.958 |
HRs-/HER2- | 4.23 | 1.11–16.09 | 0.034 |
MMG presentation of the main lesion | |||
Mass or undetected | Ref | ||
Microcalcifications ± mass | 0.29 | 0.03–2.51 | 0.263 |
MMG associated microcalcifications | |||
Absent | Ref | ||
Present | 0.84 | 0.13–5.60 | 0.855 |
US shape | 0.370 | ||
Irregular | Ref | ||
Oval | 1.11 | 0.39–3.17 | 0.846 |
Round | 5.83 | 0.49–69.80 | 0.164 |
US posterior features | 0.543 | ||
No posterior features | Ref | ||
Shadowing | 1.40 | 0.38–3.17 | 0.846 |
Enhancement | 1.92 | 0.60–6.21 | 0.275 |
US calcification | |||
No | Ref | ||
Yes | 1.34 | 0.22–8.27 | 0.751 |
MRI presentation of the main lesion | |||
Mass | Ref | ||
Non-mass enhancement | 1.18 | 0.32–4.31 | 0.807 |
MMG after NCT | |||
Residual disease | Ref | ||
Complete response | 0.90 | 0.20–4.06 | 0.890 |
US after NCT | |||
Residual disease | Ref | ||
Complete response | 2.69 | 0.79–9.19 | 0.114 |
MRI after NCT | |||
Residual disease | Ref | ||
Complete response | 5.23 | 1.53–17.85 | 0.008 |
CI, confidence interval; Ref, reference; MMG, mammography; US, ultrasound; MRI, magnetic resonance imaging.