Table 3. T2R38-IR expression in CCK, GLP-1 and PYY populations in normal and overweight/obese subjects.
Subjects | CCK-IR cells | %T2R38/ CCK-IR cells | GLP1-IR cells | %T2R38/ GLP1-IR cells | PYY-IR cells | %T2R38/ PYY-IR cells |
---|---|---|---|---|---|---|
NW n = 10 | 22.9±2.4 | 85.7±1.8* | 49.8±7.8 | 45.1±8.7 | 59±13 | 67.1±8.7 |
OW/OB n = 20 | 27.2±3.1 | 93.1±2.9* | 59.8±6.7 | 54.1±5.6 | 88.5±10.1 | 56.7±5.4 |
Values represent the mean±SEM of the average number of cells and the % of each EEC population expressing T2R38-IR.
* P< 0.03 between %T2R38/CCK-IR cells in OW/OB vs. NW subjects.