Table 1.
Some existing and ongoing human genome sequencing projects.
| Dataset | Number of individuals | Healthy/Diseases (H/D) | Exome/Genome (E, G, E+G) | Ref |
|---|---|---|---|---|
| Complete Genomics Data | 69 | H | G | 1 |
| Singapore Sequencing Malay Project | 100 | H | G | 2 |
| Genome of the Netherlands | 767 | D | G | 3 |
| 1000 Genome Project Phase 3 | 2,504 | H | E+G | 4 |
| Personal Genome Project | 4,419* | H | G | 5 |
| Exome Sequencing Project (ESP) | 6,515 | D | E | 6 |
| UK10K project | 10,000 | D | E+G | 7 |
| The Cancer Genome Atlas (TCGA) | 11,080 | H+D | E+G | 8 |
| Exome Aggregation Consortium (ExAC) | 60,706 | H+D | E | 9 |
| TOTAL | 82,772^ |
The numbers in the table are correct as of July 28th 2015.
The Personal Genome Project sets a target of sequencing 100,000 personal genomes.
This total excludes 1,851 individuals from 1000 Genomes Project Phase 3, 3,936 from the ESP and 7,601 from TCGA since they are also included in the ExAC dataset.
References
Complete Genomics: http://www.completegenomics.com/public-data/69-Genomes/
Wong, L.-P., Ong, R. T.-H., Poh, W.-T., Liu, X., Chen, P., Li, R., Lam, K. K.-Y., Pillai, N. E., Sim, K.-S., Xu, H., Sim, N.-L., Teo, S.-M., Foo, J.-N., Tan, L. W.-L., Lim, Y., Koo, S.-H., Gan, L. S.-H., Cheng, C.-Y., Wee, S., Yap, E. P.-H., Ng, P. C., Lim, W.-Y., Soong, R., Wenk, M. R., Aung, T., Wong, T.-Y., Khor, C.-C., Little, P., Chia, K.-S. & Teo, Y.-Y. Deep whole-genome sequencing of 100 southeast Asian Malays. Am J Hum Genet 92, 52–66 (2013).
Genome of the Netherlands: http://www.genoomvannederland.nl/?page_id=9
The 1000 Genomes Project Consortium. A global reference for human genetic variation. Nature (2015) (in press)
Personal Genome Project: https://my.personalgenomes.org/users
Tennessen, J. A., Bigham, A. W., O’Connor, T. D., Fu, W., Kenny, E. E., Gravel, S., McGee, S., Do, R., Liu, X., Jun, G., Kang, H. M., Jordan, D., Leal, S. M., Gabriel, S., Rieder, M. J., Abecasis, G., Altshuler, D., Nickerson, D. A., Boerwinkle, E., Sunyaev, S., Bustamante, C. D., Bamshad, M. J. & Akey, J. M. Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science (New York, N.Y.) 337, 64–9 (2012).
UK10K: http://www.uk10k.org/
The Cancer Genome Atlas Portal: https://dcc.icgc.org/
Exome Aggregation Consortium: http://exac.broadinstitute.org/faq