. Author manuscript; available in PMC: 2016 Dec 1.

Published in final edited form as: Curr Opin Struct Biol. 2015 Dec 1;35:125–134. doi: 10.1016/j.sbi.2015.11.003

Table 2.

Per-individual whole exome SNV load in the 1000 Genomes Project Phase 1 data.

	SYNONYMOUS				NON-SYNONYMOUS
	DAF <0.5%	DAF 0.5–5%	DAF >5%	Total	DAF <0.5%	DAF 0.5–5%	DAF >5%	Total
AVERAGE	295	1,014	12,892	14,201	434	1,055	10,816	12,305
YRI	547	2,468	12,190	15,205	691	2,377	10,056	13,130
CEU	175	593	13,237	14,006	298	709	11,173	12,180
CHB	218	497	13,077	13,792	355	563	11,026	11,944
JPT	240	500	13,067	13,807	387	571	11,012	11,970

The number of synonymous and non-synonymous SNVs are categorized into three ranges of derived allele frequency (DAF; defined as the allele alternative to the ancestral allele). DAF<0.5% are considered ‘rare’. Ancestry legend, YRI: Yoruba in Ibadan, Nigeria; CEU: Utah Residents (CEPH) with Northwestern European ancestry; CHB: Han Chinese in Beijing; JPT: Japanese in Tokyo, Japan.