Table 1.
Subject characteristics before and after IMM or RYGB
| IMM | RYGB | ||||||
|---|---|---|---|---|---|---|---|
| Month 0 | Month 12 | aP | Month 0 | Month 12 | aP | bP | |
| Male/Female (n) | 8/7 | - | 6/9 | - | 0.46 | ||
| Age (y) | 48.5 ± 2.1 | - | 46.9 ± 2.2 | - | 0.59 | ||
| DM duration (y) | 8.1 ± 1.7 | - | 11.2 ± 1.7 | - | 0.21 | ||
| Weight (kg) | 104.4 ± 3.9 | 92.8 ± 4.6 | 0.0001 | 105.0 ± 3.3 | 74.6 ± 3.3 | <.0001 | <.0001 |
| BMI (kg/m2) | 35.5 ± 0.9 | 31.5 ± 1.1 | 0.0002 | 36.2 ± 0.7 | 25.7 ± 0.9 | <.0001 | <.0001 |
| Total weight loss (%) | - | 11.4 ± 2.3 | - | 28.9 ± 2.2 | <.0001 | ||
| HbA1C (%) | 9.1 ± 0.2 | 6.1 ± 0.1 | <.0001 | 9.7 ± 0.2 | 6.4 ± 0.3 | <0.0001 | 0.49 |
| DM meds (n/subject) | 4.6 ± 0.3 | 4.6 ± 0.3 | 1 | 4.1 ± 0.7 | 2.5 ± 0.5 | 0.07 | 0.11 |
| HOMA-IR (mmol × mU × L−2) | 13.0 ± 2.5 | 7.0 ± 1.7 | 0.08 | 14.1 ± 3.6 | 2.1 ± 0.9 | 0.002 | 0.18 |
| Matsuda Index (1/(mmol/L)2*(pmol/L)2) | 1.9 ± 0.3 | 5.7 ± 1.7 | 0.03 | 3.6 ± 1.0 | 11.1 ± 1.6 | 0.0003 | 0.10 |
Values represent mean ± SEM.
a
P within group change;
b
P difference in the change over time between groups; any significant differences (P<0.05) between groups at the same time-point are indicated in bold.