Table 2. Clot lysis times (seconds) from thromboelastography and turbidimetry.
| Value | Healthy Control (Spec) | Diabetes Mellitus (Spec) | Obese Metabolic Syndrome (Spec) | TOPCOAT (Spec) | Total Sample (Spec) | Healthy Control (TEG) | Diabetes Mellitus (TEG) | Obese Metabolic Syndrome (TEG) | TOPCOAT (TEG) | Total Sample (TEG) |
|---|---|---|---|---|---|---|---|---|---|---|
| Valid data (N) | 20 | 10 | 10 | 76 | 116 | 20 | 10 | 10 | 76 | 116 |
| Mean | 4,898 | 7,243* | 11,296* | 5,014 | 5,369 | 4,741 | 10,529* | 11,296* | 7,319* | 7,494 |
| SD | 920 | 1,907 | 4,914 | 1,657 | 1,770 | 1,029 | 4,561 | 4,914 | 4,735 | 4,659 |
| Upper quartile | 5,319 | 9,303 | 8,465 | 6,284 | 6,574 | 5,440 | 15,145 | 15,145 | 12,449 | 12,449 |
| Median | 4,685 | 7,308 | 7,235 | 4,628 | 5,018 | 4,703 | 11,225 | 14,925 | 5,095 | 5,363 |
| Lower quartile | 4,441 | 5,364 | 6,088 | 3,739 | 4,085 | 3,842 | 5,728 | 6,039 | 3,780 | 4,081 |
| Centile 95 | 7,145 | 9,280 | 9,935 | 8,344 | 9,181 | 6,869 | 15,145 | 15,145 | 15,145 | 15,145 |
| Centile 10 | 3,465 | 4,830 | 3,765 | 2,735 | 2,957 | 3,013 | 4,595 | 4,285 | 2,613 | 2,633 |
*p < 0.05 from one-way ANOVA with Dunnett’s comparison with control
Abbreviations: Spec-spectrophotometry (turbidimetric method); TEG-Thromboelastography; TOPCOAT-tenecteplase or placebo: cardiopulmonary outcomes at three months; SD-Standard deviation.