Fig. 7.

In vitro and in vivo toxicity study of rNGO-PEG/ICG. a Cytotoxicity of rNGO-PEG/ICG (with 0–100 μg mL⁻¹) against Hela cells by CCK-8 method. Cells were incubated with rNGO-PEG/ICG for 24 and 48 h, respectively. b Representative H&E-stained images of major organs including the heart, liver, spleen, kidney, and lung collected from mice sacrificed 7 days after injection of rNGO-PEG/ICG