Table 2.
Top SNPs from the meta-analysis of GWA results in 29 discovery cohorts for extraversion, and their replication in the GS:SFHS cohort, in the Genetics of Personality Consortium
SNP | Chr_BP | Alleles | Closest gene | Discovery results | Replication results | ||||
---|---|---|---|---|---|---|---|---|---|
Effect | SE | P-value | Effect | SE | P-value | ||||
rs2024488 | 2_217662968 | A/G | LOC101928250 | −0.0303 | 0.0059 | 2.939 x 10−7 | 0.0285 | 0.0164 | 0.08244 |
rs2712162 | 2_217661788 | T/C | LOC101928250 | −0.0300 | 0.0059 | 3.872 x 10−7 | 0.0278 | 0.0164 | 0.08947 |
rs797182 | 12_10900487 | A/G | <NA> | −0.0277 | 0.0056 | 6.673 x 10−7 | −0.0135 | 0.0153 | 0.37721 |
rs8010306 | 14_37150160 | A/G | SLC25A21 | 0.0629 | 0.0128 | 8.730 x 10−7 | 0.0180 | 0.0314 | 0.56650 |
rs117292860 | 19_2227621 | A/C | DOT1L | 0.0553 | 0.0113 | 9.191 x 10−7 | −0.0350 | 0.0239 | 0.14368 |