The process of information provision as part of a national bloodspot screening programme, with an increasing emphasis on expanding the programme to include more conditions, is likely to have implications in terms of healthcare resource use and also subsequent health and non-health outcomes.

Few economic evaluations of NBSPs attempt to quantify the cost of providing information about the programme, or the impact of this information provision on parents and newborns.

Research is needed to generate robust data on the actual cost of information provision for healthcare services, the impact of NBSPs on subsequent use of healthcare services and the impact on parents’ health status and ability to make an informed decision in the context of expanded NBSPs.