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. 2015 Nov 25;149(2):396–410. doi: 10.1093/toxsci/kfv250

FIG. 1.

FIG. 1.

Aroclor 1260 exposure altered hepatic expression of Car and Pxr target genes. Hepatic mRNA expressions for (A), Car, (B) Cyp2b10 (Car target gene), (C) Pxr, (D) Cyp3a11 (Pxr target gene), and (E) Ugt1a1 (Pxr/Car target gene). Values are mean ± SEM, P < .05, a- Δ due to Aroclor 1260 exposure within genotype, b, b*- Δ between WT and Car−/− without or with Aroclor 1260 exposure, c, c*- Δ between WT and Pxr−/− without or with Aroclor 1260 exposure, d, d*- Δ between Car and Pxr ablation without or with Aroclor 1260 exposure.