Table 3.

Simulation cases used to determine the necessity of convective transport mechansims to explain perivascular drainage.

Case	Diffusion coefficient D*	Bulk flow velocity in white matter u	Perivascular drainage velocity |ub|	Uptake rate kb	Pe
A1	D*	0	0	0	0
A2	5·D*	0	0	0	0
A3	10·D*	0	0	0	0
B1	D*	u	0	0	11.08 (u)
B2	D*	5·u	0	0	55.38 (u)
B3	D*	10·u	0	0	110.76 (u)
C1	D*	u	ub	kb	527.22 (ub)
C2	D*	u	ub/2	kb	263.61 (ub)
C3	D*	u	ub/2	kb/10	263.61 (ub)
C4	5·D*	u	ub/2	kb/10	105.44 (ub)

D^* = 8.7 × 10⁻¹¹ m² s⁻¹, |u| = 1.75 × 10⁻⁷ m s⁻¹, |u_b = 8.33 × 10⁻¹¹ m s⁻¹, k_b = 2.5 × 10⁻⁴ s⁻¹ (Table 1).