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Akt regulates incomplete cytokinesis and formation of multinucleated osteoclasts. A, percentage of cells that went through incomplete cytokinesis (magenta) or cytokinesis (yellow). dTg-BMMs were cultured with M-CSF (60 ng/ml) and RANKL in the presence of the indicated reagents. Cells that did not enter mitotic phase are shown in gray. Data shown as percentage of cells pooled from two independent experiments.
