Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Dec 14;291(7):3668–3681. doi: 10.1074/jbc.M115.699801

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

PMC Copyright notice

FIGURE 3. — Structural comparison of Rv2837c. A, structural comparison of Rv2837c and M. smegmatis MSMEG_2630. The cartoon views of Rv2837c and MSMEG_2630 are colored cyan and wheat. B, effects of mutants in metal ligands and the DHH motif on c-di-AMP hydrolysis. C, CD spectra of Rv2837c and its mutants. In general, alanine replacement mutagenesis was constructed. The glycine was replaced by arginine. D, structural comparison of Rv2837c and Rv2837c/pApA complex. The cartoon views of Rv2837c and Rv2837c/pApA complex are colored cyan and orange, respectively. The residues in contact with the metal ions and pApA are shown as sticks. All metal ions are shown as spheres and colored by the structure.