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. 2016 Feb 12;6:20913. doi: 10.1038/srep20913

Table 2. Clinical characteristics and EGFR T790M ctDNA status in plasma of 117 patients.

  Total T790M ctDNA in plasma p-value
T790M +ve T790M −ve
N 117 55 62  
Age       1
<=60 66 31 35  
>60 51 24 27  
Sex       0.1293
Female 71 29 42  
Male 46 26 20  
Histopathological type       0.1698
Adenocarcinoma 108 53 55  
Non-adeno 9 2 7  
Clinical stage       0.0677
Recurrent 21 6 15  
Stage IV 91 48 43  
Stage IIIb 5 1 4  
Smoking       0.3918
Yes 29 16 13  
No 88 39 49  
TKI line of treatment       0.6688
First line 29 15 14  
Second line or after 88 40 48  
Post TKI PD therapy       0.6467
TKI alone 55 24 31  
TKI + chemo 52 25 27  
Others 10 6 4