Table 5. Probes targeting functional variants in genes in the complement cascade.
| Gene symbol | Locusa | # Probes | Evidence for CNV?b |
|---|---|---|---|
| Daf2 | 1: 130.4 | 3 | |
| Cd55 | 1: 130.4 | 4 | |
| Cd46 | 1: 195.1 | 2 | |
| Serping1 | 2: 84.8 | 1 | 19270705 |
| Cd59b | 2: 104.1 | 7 | 20308636, 21921910 |
| Cd59a | 2: 104.1 | 2 | 20308636 |
| Fstl5 | 3: 76.4 | 1 | |
| Klhl32 | 4: 24.7 | 1 | |
| C8a | 4: 104.9 | 2 | |
| C1qb | 4: 136.9 | 3 | |
| Masp2 | 4: 148.6 | 4 | |
| Depdc5 | 5: 32.9 | 1 | |
| Grm8 | 6: 27.4 | 1 | |
| C1ra | 6: 124.5 | 6 | |
| C1s1 | 6: 124.5 | 10 | 19270704, 19270705, 21921910, 17989247 |
| C1rb | 6: 124.6 | 3 | 19270705, 21921910 |
| C1s2 | 6: 124.6 | 7 | |
| Cfd | 10: 79.9 | 2 | 19270705 |
| Pcdh9 | 14: 93.2 | 1 | |
| C9 | 15: 6.5 | 2 | |
| Masp1 | 16: 23.5 | 2 | |
| C4b | 17: 34.7 | 16 | 21921910 |
| C4a | 17: 34.8 | 12 | 21921910, 17989247 |
| C2 | 17: 34.9 | 1 | |
| C3 | 17: 57.2 | 4 | 21921910 |
a
Denoted as chromosome: position in Mb, in GRCm38/mm10 coordinates.
b
Pubmed IDs of reports of CNVs kb in size overlapping each locus. Key to references: 17989247, Cutler et al. (2007); 19270704, Cahan et al. (2009); 19270705, Henrichsen et al. (2009); 20308636, Quinlan et al. (2010); 21921910, Keane et al. (2011); 22916792, Wong et al. (2012).