TABLE 7.

Occupancy of protein binding sites in Snf1-dependent mRNAs after the addition of glucose to starved cells

Region	Occupancya	P valueb	No. of bound sites in:
			Snf1-dependent genes	Random genesd
			Countc	Avg count	SD
5′-UTR	Increased	3.45E−16	18	6.2	2.9
	Decreased	6.22E−01	1	1.1	1.2
3′-UTR	Increased	3.14E−09	22	11	5.9
	Decreased	1.22E−01	2	2.6	1.9
Coding sequence	Increased	3.81E−02	73	67	14
	Decreased	9.42E−05	19	14	5.6
Intron	Increased	1.95E−04	0	1.5	1.6
	Decreased	8.30E−02	0	0.25	0.68

^aProtein binding sites exhibiting a threefold increase or decrease in binding site reads per million normalized to gene reads per kilobase per million, as defined in Freeberg et al. (41).

^bThe probability that the number of Snf1-dependent genes containing one or more RBP binding sites occurred by random chance. Significant enrichment is seen at P values of less than 1 × 10⁻⁶.

^cThe number of Snf1-dependent genes coding for mRNAs with sequences identified by gPAR-CLIP as occupied.

^dStatistics for RBP binding sites in 24 sets of 34 random Snf1-independent mRNAs.