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. 2016 Feb 12;17:86. doi: 10.1186/s12859-016-0916-x

Table 2.

Computing time (seconds) of four methods with sample size 200 and 1000 permutations

NetDifM NetDifMpm VEWDM Yates’D
Network1 0.0015 0.91 0.76 3.83
Network2 0.0034 2.04 1.07 6.95
Network3 0.0064 3.92 2.16 12.37

Network1 ten vertices and 21 edges; Network2 20 vertices and 45 edges;

Network3 40 vertices and 54 edges