Pathogenicity islands and T3SS2. tdh PAI (A) and trh PAI (B) are the two canonical genomic islands present in clinical isolates of V. parahaemolyticus. The presence or absence of these islands is strongly correlated with the presence of the tdh and trh genes. In three of the four tdh- and trh-negative isolates, these genes are entirely absent. (C) In the fourth tdh- and trh-negative isolate, 10-4328, a trh PAI including a partial trh1 gene is mostly present. Abbreviations: neg, negative; pos, positive.