Table 3.
0 µg DEP | 10 µg DEP | 100 µg DEP | ||||
---|---|---|---|---|---|---|
Wild-type | Nep-null | Wild-type | Nep-null | Wild-type | Nep-null | |
Inflammatory cells | ||||||
Total cells | 41.17 ± 2.93 | 45.83 ± 3.66 | 70.29 ± 11.69a | 130.50 ± 17.09a,b,c | 100.00 ± 9.21a | 153.43 ± 10.61a,b,c |
Macrophages | 37.86 ± 2.67 | 43.16 ± 3.57 | 65.43 ± 12.21 | 120.07 ± 18.47a,b,c | 88.90 ± 10.35a | 135.18 ± 5.6a,b,c |
Granulocytes | 1.40 ± 0.33 | 1.21 ± 0.32 | 2.51 ± 0.44 | 4.80 ± 0.94 | 4.07 ± 0.67 | 6.24 ± 1.06b |
Lymphocytes | 1.91 ± 0.22 | 1.47 ± 0.29 | 3.61 ± 0.87 | 5.63 ± 1.64 | 7.03 ± 1.79 | 10.09 ± 2.95b |
Epithelial cells | 1.77 ± 0.65 | 1.95 ± 0.69 | 13.01 ± 2.34a | 19.50 ± 4.43a,b | 19.35 ± 3.98a | 37.71 ± 6.42a,b,c |
P < 0.05 compared to wild-type mice at 0 µg DEP exposure.
P < 0.05 compared to Nep-null mice at 0 µg DEP exposure.
P < 0.05 compared to wild-type mice given the same DEP dose.