Table 5.
Up- and Downregulated Genes in NEP-Knockdown Human Airway Epithelial Cells
| Probe Set ID | Unigene IDa |
Gene Symbol |
Gene Title | Fold (log) ([siRNA]/[MOCK]) |
|---|---|---|---|---|
| 231578_at | Hs.62661 | GBP1 | Guanylate binding protein 1 | 1.27 |
| 1554997_a_at | Hs.196384 | PTGS2 | Prostaglandin-endoperoxide synthase 2 | 1.28 |
| 204897_at | Hs.199248 | PTGER4 | Prostaglandin e receptor 4 (subtype ep4) | 1.81 |
| 202393_s_at | Hs.435001 | KLF10 | Kruppel-like factor 10 | 1.48 |
| 219995_s_at | Hs.653124 | ZNF750 | Zinc finger protein 750 | 1.44 |
| 229450_at | Hs.47338 | IFIT3 | Interferon-induced protein with tetratricopeptide repeats 3 | 1.52 |
| 211506_s_at | Hs.624 | IL8 | Interleukin 8 | 1.89 |
| 205207_at | Hs.654458 | IL6 | Interleukin 6 | 1.73 |
| 201565_s_at | Hs.180919 | ID2 | Inhibitor of dna binding 2 | 1.43 |
| 202672_s_at | Hs.460 | ATF3 | Activating transcription factor 3 | 1.64 |
| 202241_at | Hs.444947 | TRIB1 | Tribbles homolog 1 (drosophila) | 1.75 |
| 238688_at | Hs.133892 | TPM1 | Tropomyosin 1 (alpha) | 1.66 |
| 1555372_at | Hs.469658 | BCL2L11 | Bcl2-like 11 (apoptosis facilitator) | 1.67 |
| 222662_at | Hs.458513 | PPP1R3B | Protein phosphatase 1 | 1.74 |
| 222162_s_at | Hs.643357 | ADAMTS1 | Adam metallopeptidase with thrombospondin type 1 motif | 2.12 |
| 234608_at | Hs.436367 | LAMA3 | Laminin 3 | 2.27 |
| 206115_at | Hs.534313 | EGR3 | Early growth response 3 | 3.81 |
| 238177_at | Hs.585128 | SLC6A19 | Solute carrier family 6 (neutral amino acid transporter) | −1.09 |
| 1558814_s_at | Hs.482873 | TMED5 | Transmembrane emp24 protein transport domain containing 5 | −1.04 |
| 1565484_x_at | Hs.488293 | EGFR | Epidermal growth factor receptor | −1.06 |
| 1560878_at | Hs.696346 | SYT15 | Synaptotagmin xv | −1.03 |
| 236033_at | Hs.56281 | ASB12 | Ankyrin repeat and socs box-containing 12 | −1.02 |
| 1565537_at | Hs.526396 | NKX1-1 | Nk1 homeobox 1 | −1.04 |
| 228691_at | Hs.505202 | BICD1 | Bicaudal d homolog 1 (drosophila) | −1.04 |
| 1553657_at | Hs.10697 | VWA3A | von Willebrand factor A domain containing 3A | −1.03 |
| 243534_at | Hs.652240 | CC2D2B | Coiled-coil and C2 domain containing 2B | −1.05 |
| 1565483_at | Hs.488293 | EGFR | Epidermal growth factor receptor | −1.03 |
| 1554400_at | Hs.584808 | TCTE3 | T-complex-associated-testis-expressed 3 | −1.03 |
| 220421_at | Hs.189109 | BTNL8 | Butyrophilin-like 8 | −1.06 |
| 1568513_x_at | Hs.654496 | IL23A | Interleukin 23 | −1.03 |
| 214414_x_at | Hs.654744 | HBA2 | Hemoglobin | −1.01 |
a
Per Avadis software platform (Strand Life Sciences, San Francisco, CA).