Table 7.

Gene Downregulation After DEP Exposure in Cultured Human Airway Epithelial Cells

Probe Set ID	Unigene IDa	Gene Symbol	Gene Title	Fold (log)b
				10 µg/cm2	40 µg/cm2
219270_at	Hs.155569	CHAC1	ChaC	−0.11	−23.60
206085_s_at	Hs.19904	CTH	Cystathionase (cystathionine gamma-lyase)	3.12	−18.20
1555788_a_at	Hs.516826	TRIB3	Tribbles homolog 3 (Drosophila)	1.78	−16.33
217168_s_at	Hs.146393	HERPUD1	Homocysteine-inducible	2.05	−14.18
238760_at	Hs.213264	YARS	Tyrosyl-tRNA synthetase	0.65	−13.95
223062_s_at	Hs.494261	PSAT1	Phosphoserine aminotransferase 1	1.41	−11.09
220892_s_at	Hs.494261	PSAT1	Phosphoserine aminotransferase 1	0.22	−13.13
209383_at	Hs.505777	DDIT3	DNA-damage-inducible transcript 3	0.49	−11.42
241905_at	Hs.175343	PIK3C2A	Phosphoinositide-3-kinase	1.16	−8.36
213672_at	Hs.632707	MARS	Methionyl-tRNA synthetase	2.43	−7.78
1554008_at	Hs.120658	OSMR	Oncostatin M receptor	0.22	−7.09
205047_s_at	Hs.489207	ASNS	Asparagine synthetase	0.14	−10.87
223195_s_at	Hs.469543	SESN2	Sestrin 2	0.78	−6.36
1554933_at	Hs.658434	PSIP1	PC4 and SFRS1 interacting protein 1	0.00	−5.86
243299_at	Hs.666703		Transcribed locus	1.71	−5.78
202388_at	Hs.78944	RGS2	Regulator of G-protein signaling 2	−1.00	−7.41
239451_at	Hs.658060		CDNA FLJ26407 fis	0.06	−6.45
222763_s_at	Hs.620490	WDR33	WD repeat domain 33	−0.40	−5.31
220195_at	Hs.458312	MBD5	Methyl-CpG binding domain protein 5	0.18	−5.04
238311_at	Hs.668598		Transcribed locus	1.19	−5.11
204203_at	Hs.429666	CEBPG	CCAAT/enhancer binding protein (C/EBP)	0.03	−5.48
232017_at	Hs.50382	TJP2	Tight junction protein 2 (zona occludens 2)	−0.54	−5.95
206884_s_at	Hs.534699	SCEL	Sciellin	0.77	−4.23
244822_at	Hs.473648	GART	Phosphoribosylglycinamide formyltransferase	0.24	−5.74
243543_at	Hs.655159		Transcribed locus	−0.49	−4.88
1556602_at	Hs.663643		CDNA FLJ36293 fis	0.91	−3.93
233406_at	Hs.667905		CDNA FLJ12038 fis	1.43	−6.13
218943_s_at	Hs.190622	DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	−0.03	−4.83
203438_at	Hs.233160	STC2	Stanniocalcin 2	1.94	−4.76
230097_at	Hs.473648	GART	Phosphoribosylglycinamide formyltransferase	−0.30	−6.62
244075_at	Hs.380900		Transcribed locus	−0.15	−4.79
244803_at	Hs.658791		Transcribed locus	0.74	−4.64
229999_at	Hs.432355		Full length insert cDNA clone ZE12A08	−0.84	−3.77
238875_at	Hs.656795		Clone HLS_IMAGE_731119 mRNA sequence	0.48	−6.35
243332_at	Hs.670186		Transcribed locus	0.82	−4.46
236244_at	Hs.166463	HNRNPU	Heterogeneous nuclear ribonucleoprotein U	−1.00	−3.59
215470_at			General transcription factor IIH	−0.98	−3.67
240206_at	Hs.481860	TARS	Threonyl-tRNA synthetase	−0.78	−3.39
236149_at	Hs.677583		Transcribed locus	0.77	−2.96
242784_at	Hs.665271		Transcribed locus	−0.37	−3.31
241433_at	Hs.696152	RCOR3	REST corepressor 3	−1.00	−3.32
221577_x_at	Hs.616962	GDF15	Growth differentiation factor 15	−0.30	−4.77
206411_s_at	Hs.159472	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	−0.75	−3.41
218986_s_at	Hs.591710	FLJ20035	Hypothetical protein FLJ20035	−0.66	−3.33
233436_at	Hs.657656	MTBP	Mdm2	−0.16	−2.88
242712_x_at	Hs.652430	RANBP2	RAN binding protein 2	−0.30	−3.59
243631_at	Hs.659894	LOC642333	Similar to M-phase phosphoprotein	−0.06	−3.84
237839_at	Hs.672300		Transcribed locus	0.02	−3.39
238348_x_at	Hs.667738		Transcribed locus	−0.67	−4.14
230375_at	Hs.520287	SFRS18	Splicing factor	0.21	−4.04
238357_at	Hs.282901	RBM39	RNA binding motif protein 39	−1.00	−2.82
230516_at	Hs.87385	C7orf30	Chromosome 7 open reading frame 30	0.01	−3.04
238666_at	Hs.659573		Transcribed locus	−0.37	−3.75
239358_at	Hs.655048		Transcribed locus	−0.65	−3.06
236696_at	Hs.596572	SR140	U2-associated SR140 protein	0.38	−2.36
237379_at	Hs.325838	KIAA1542	CTD-binding SR-like protein rA9	−1.00	−1.93
217616_at	Hs.613488		Transcribed locus	−1.00	−1.78
1559691_at	Hs.684424		CDNA clone IMAGE:3869664	−0.41	−2.12
203434_s_at	Hs.307734	MME (NEP)	Membrane metallo-endopeptidase (neprilysin)	−0.53	−0.76

^aPer Avadis software platform (Strand Life Sciences, San Francisco, CA).