Table 1.

Physicochemical characteristics of AMCA-labeled particles determined by dynamic laser light scattering techniques in water

Sample name	Averaged HD (nm)	PdI	ZP (mV)
AMCA-PLGA MP	1,068±46	0.21±0.03	−34.0±1.1
Chi-AMCA-PLGA MP	1,170±145	0.24±0.06	−4.0±1.6
AMCA-PLGA NP	234±10	0.10±0.05	−32.6±3.8
Chi-AMCA-PLGA NP	512±163	0.44±0.19	−10.1±2.4

Note: Data are shown as the mean ± SD of three independent experiments.

Abbreviations: AMCA, 7-amino-4-methyl-3-coumarinylacetic acid; Chi, chitosan; HD, hydrodynamic diameter measured by photon correlation spectroscopy; MP, microparticles; NP, nanoparticles; PdI, polydispersity index; PLGA, poly(d,l-lactide-co-glycolide); SD, standard deviation; ZP, zeta potential.