Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
CDCP1 promotes cancer cell proliferation (generally under non-adherent conditions), survival and migration, and mediates resistance to chemo- and targeted-therapies. CDCP1 expression at the cell surface is increased by ligand activation of EGFR signaling, constitutively activated mutant Ras (Ras*), and hypoxia (O2↓). Scissors represent arginine/lysine specific serine proteases that cleave and activate CDCP1.
