Table 2. Top 10 up- and down-regulated gene probes in HepG2 cells treated with 10 μM GSK343 for 6 h.
| Probe ID | Gene Symbol | Description | Fold Change |
|---|---|---|---|
| PH_hs_0028852 | MT1B | metallothionein 1B | 4.465048 |
| PH_hs_0006434 | VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 3.608639 |
| PH_hs_0006739 | TMEM63C | transmembrane protein 63C | 3.248965 |
| PH_hs_0042917 | MT1M|MT1JP | metallothionein 1Mmetallothionein 1J, pseudogene | 3.151759 |
| PH_hs_0023522 | MMP25 | matrix metallopeptidase 25 | 1.978682 |
| PH_hs_0043618 | LRTOMT | leucine rich transmembrane and 0-methyltransferase domain containing | 1.926359 |
| PH_hs_0049631 |
MT1IP|MT1X |MT1E|MT1A |MT2A|MT1B| |MT1L|MT1H |
metallothionein 1I, pseudogenemetallothionein 1X|metallothionein 1E|metallothionein 1A|metallothionein 2A|metallothionein 1B|metallothionein 1L (gene/pseudogene)|metallothionein 1H | 1.809486 |
| PH_hs_0036496 | TWIST2 | twist basic helix-loop-helix transcription factor 2 | 1.751665 |
| PH_hs_0045784 | MT1A | metallothionein 1A | 1.659662 |
| PH_hs_0018184 | MT1X | metallothionein 1X | 1.651276 |
| PH_hs_0032121 | ARL6 | ADP-ribosylation factor-like 6 | −4.519956 |
| PH_hs_0036082 | HIST1H3J | histone cluster 1, H3j | −3.96339 |
| PH_hs_0042831 | SPINK14 | serine peptidase inhibitor, Kazal type 14 (putative) | −2.858793 |
| PH_hs_0032938 | C16orf47 | chromosome 16 open reading frame 47 | −2.674934 |
| PH_hs_0002738 | PGR | progesterone receptor | −2.653247 |
| PH_hs_0019504 | MZB1 | marginal zone B and B1 cell-specific protein | −2.615926 |
| PH_hs_0031538 | RNASE11 | ribonuclease, RNase A family, 11 (non-active) | −2.606224 |
| PH_hs_0031319 | SLA | Src-like-adaptor | −2.571705 |
| PH_hs_0042528 | OR51Q1 | olfactory receptor, family 51, subfamily Q, member 1 | −2.56117 |
| PH_hs_0045727 | FLT1 | fms-related tyrosine kinase 1 | −2.365311 |
MT genes were highlighted in bold.