Table 1. Patient- and tumor characteristics according to age groups.
| Early onset EAC n = 28 (%) |
Conventional EAC n = 27 (%) |
p-value (χ2) | |
|---|---|---|---|
| Mean Age (sd) | 37.21(3.023) | 74.63 (4.395) | <0.001 (T-test) |
| Gender | 0.249 | ||
| Male | 25 (89.3) | 21 (77.8) | |
| Female | 3 (10.7) | 6 (22.2) | |
| Tumor type | 0.718 | ||
| EAC | 16 (57.1) | 17 (63.0) | |
| GEJAC | 9 (32.1) | 9 (33.3) | |
| Cardia | 2 (7.1) | 1 (3.6) | |
| Unknown | 1 (3.7) | 0 (0) | |
| TNM stage* | 0.350 | ||
| IA | 5 (17.9) | 3 (11.1) | |
| IB | 3 (10.7) | 0 (0) | |
| IIA | 0 (0) | 1 (3.7) | |
| IIB | 2 (7.1) | 7 (25.9) | |
| IIIA | 9 (32.1) | 7 (25.9) | |
| IIIB | 3 (10.7) | 2 (7.4) | |
| IIIC | 5 (17.9) | 6 (22.2) | |
| IV | 1 (3.6) | 1 (3.7) | |
| Differentiation grade | 0.233 | ||
| High grade dysplasia | 0 (3.6) | 0 (0) | |
| Good | 4 (14.3) | 0 (0) | |
| Moderate | 11 (39.3) | 16 (59.3) | |
| Poor | 9 (32.1) | 9 (33.3) | |
| Unknown | 4 (14.3) | 2 (7.4) |
EAC= esophageal adenocarcinoma
GEJAC= gastro-esophageal junction adenocarcinoma
*
According to the classification of the American Joint Committee on Cancer (AJCC) Staging Manual 7th edition.