Table 3.
Compound ID | Structure | IUPAC name | MW (g/mole) | IC50 (nM) | r2 |
---|---|---|---|---|---|
MMV666080 | N-[(8-hydroxyquinolin-7-yl)-phenylmethyl]benzamide | 354.4 | 14.9 | 0.97 | |
MMV396693 | 2-[(10-methylphenazin-10-ium-2-yl)amino]ethanol | 254.31 | 53.4 | 0.97 | |
MMV007564 | 1-[1-[(4-methylphenyl)methyl]benzimidazol-2-yl]-N-(thiophen-2-ylmethyl)piperidine-4-carboxamide | 444.59 | 60.8 | 0.95 | |
MMV666023 | 2-{2-[(4-nitrophenyl)methylidene]hydrazin-1-yl}-1H-1,3-benzodiazole | 453.54 | 91.7 | 0.93 | |
MMV007396 | N-[2-[2-(2-methylphenoxy)ethylsulfanyl]-1,3-benzothiazol-6-yl]thiophene-2-carboxamide | 426.57 | 119.8 | 0.94 | |
MMV666607 | 2-{2-[(4-nitrophenyl)methylidene]hydrazin-1-yl}-1H-1,3-benzodiazole | 281.27 | 133.6 | 0.85 | |
MMV007557 | N-[2-(3,4-dimethoxyphenyl)ethyl]-5-(3,5-dimethylpiperidin-1-yl)sulfonyl-2-(4-fluorophenyl)sulfanylbenzamide | 586.74 | 179.9 | 0.86 | |
MMV667486 | 1-(4-ethoxyphenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine | 261.32 | 192.8 | 0.94 | |
MMV008149 | 1-[(4-fluorophenyl)methyl]-N-(furan-2-ylmethyl)-2,3-dimethylindole-5-carboxamide | 376.42 | 228.9 | 0.83 | |
MMV000444 | 1-(2-imino-3-pentylbenzimidazol-1-yl)-3-(3-methylphenoxy)propan-2-ol | 367.48 | 267.2 | 0.91 | |
MMV666069 | ({1-[2-(4-methoxyphenyl)ethyl]piperidin-4-ylmethyl)(methyl)[(1-phenyl-1H-pyrazol-4-yl)methyl]amine | 418.57 | 366.5 | 0.92 | |
MMV007881 | N-[4-(dibutylsulfamoyl)phenyl]furan-2-carboxamide | 378.49 | 417.7 | 0.81 | |
MMV006169 | N-phenyl-N′-(phenylmethyl)quinazoline-2,4-diamine | 326.39 | 466.6 | 0.90 | |
MMV665827 | ethyl 1-ethyl-6-fluoro-4-oxo-7-piperidin-1-ylquinoline-3-carboxylate | 356.40 | 477.7 | 0.81 |
IUPAC = International Union of Pure and Applied Chemistry; MMV = Medicines for Malaria Venture; MW = molecular weight.