Table 2.

Associations between plasma phospholipid PUFAs in relation to incident mobility disability risk

	Men n = 264			Women n = 292
	Model 1 (OR (95% CI))	Model 2 (OR (95% CI))	Model 3 (OR (95% CI))	Model 1 (OR (95% CI))	Model 2 (OR (95% CI))	Model 3 (OR (95% CI))
Long chain n - 3 PUFAs	0.94 (0.49; 1.78)	1.07 (0.54; 2.14)	1.24 (0.57; 2.70)	0.47 (0.25; 0.89)	0.49 (0.26; 0.93)	0.48 (0.25; 0.93)
Eicosapentaenoic acid	0.83 (0.42; 1.64)	0.96 (0.45; 2.01)	1.05 (0.47; 2.32)	0.53 (0.28; 1.03)	0.55 (0.28; 1.07)	0.55 (0.28; 1.10)
Docosapentaenoic acid	0.79 (0.43; 1.45)	0.82 (0.41; 1.60)	0.85 (0.43; 1.70)	1.02 (0.67; 1.56)	1.07 (0.70; 1.66)	1.12 (0.71; 1.74)
Docosahexaenoic acid	1.11 (0.60; 2.08)	1.22 (0.65; 2.29)	1.46 (0.70; 3.04)	0.45 (0.25; 0.81)	0.46 (0.26; 0.84)	0.45 (0.24; 0.83)
Alpha-linoleic acid	1.16 (0.69; 1.93)	1.12 (0.65; 1.93)	1.11 (0.64; 1.94)	1.36 (0.94; 1.97)	1.42 (0.96; 2.09)	1.40 (0.95; 2.07)
Long chain n - 6 PUFAs	0.92 (0.52; 1.65)	0.79 (0.42; 1.48)	0.72 (0.37; 1.41)	1.35 (0.83; 2.19)	1.32 (0.81; 2.16)	1.29 (0.78; 2.15)
Linoleic acid	1.11 (0.60; 2.06)	0.93 (0.46; 1.86)	0.90 (0.44; 1.83)	1.32 (0.83; 2.12)	1.29 (0.80; 2.07)	1.27 (0.78; 2.05)
Arachidonic acid	0.69 (0.34; 1.39)	0.69 (0.34; 1.39)	0.60 (0.28; 1.31)	1.05 (0.67; 1.64)	1.05 (0.65; 1.70)	1.03 (0.63; 1.67)

Abbreviations: CI, confidence interval; OR, odds ratio; PUFA, polyunsaturated fatty acids. Mobility disability was defined as having much difficulty or unable to walk 500 m and/or climb 10 steps at follow-up. Seventeen men and twenty-five women reported having mobility disability. Model 1 was adjusted for age, education, waist circumference and follow-up time. Model 2 was adjusted for model 1 plus smoking status, physical activity, hypertension, diabetes mellitus and heart disease. Model 3 was adjusted for model 2 plus serum vitamin D.