Table 3. Semiquantitative analysis of tubular necrosis, interstitial fibrosis, mononuclear cell infiltration in control, Sham, UO, and UO+ML treated rats.
| Tubular necrosis | Interstitial fibrosis | Mononuclear cell infiltration | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | |||
| Control | 8 | 8 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 7 | 1 | 0 | 0 | ||
| Sham | 8 | 8 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 7 | 1 | 0 | 0 | ||
| UOa | 8 | 0 | 1 | 4 | 3 | 0 | 2 | 3 | 3 | 0 | 2 | 2 | 4 | ||
| UO+MLb | 8 | 1 | 5 | 1 | 1 | 2 | 5 | 1 | 0 | 1 | 6 | 1 | 0 | ||
Score 0 = no degeneration, 1 = mild degeneration, 2 = moderate degeneration, and 3 = severe degeneration
a Statistical significant difference from the Sham group
b Statistical significant difference from the UO group and P < 0.05