TABLE 2.
Baseline Psychometric, Platelet Aggregation, and Cardiovascular Hemodynamics
Baseline Psychometric Parameters
| |||
---|---|---|---|
Females (n = 52) |
Males (n = 250) |
p Value | |
H/o depression | 31.48 | 10.16 | <0.001 |
Baseline sadness | 13.6 (7.7, 19.5) | 6.7 (4.8, 8.6) | 0.007 |
Baseline tension | 22.7 (15.8, 29.6) | 15.4 (12.9, 17.9) | 0.02 |
Baseline frustration* | 15.6 (7.8, 23.5) | 7.2 (5.3, 9.2) | 0.18 |
Baseline calm | 74.8 (67.8, 81.9) | 85.5 (83.1, 88.0) | <0.001 |
Baseline in-control | 77.4 (70.1, 84.6) | 82.1 (79.1, 85.0) | 0.2 |
Cook-Medley Hostility score | 9.6 (8.2, 11.0) | 10.4 (9.8, 11.0) | 0.3 |
State anxiety | 31.4 (28.9, 34.0) | 28.3 (27.2, 29.3) | 0.02 |
Trait anxiety | 38.6 (35.4, 41.9) | 33.0 (31.8, 34.2) | <0.001 |
Perceived stress | 26.6 (24.6, 28.5) | 22.1 (21.3, 23.0) | <0.001 |
BDI II | 10.9 (8.6, 13.1) | 7.9 (7.1, 8.7) | 0.004 |
CESD score | 33.7 (31.1, 36.6) | 29.4 (28.4, 30.4) | <0.001 |
| |||
Resting Platelet Aggregation: Area Under the Curve
| |||
Females (n = 38) |
Males (n = 238) |
p Value | |
| |||
Epinephrine 10 μm | 191.3 (149.8, 232.8) | 137.9 (125.1, 150.8) | 0.004 |
Collagen 10 μm | 292.8 (260.0, 325.6) | 273.1 (260.3, 285.9) | 0.26 |
ADP 5 μm | 239.6 (199.7, 279.5) | 248.9 (234.6, 263.3) | 0.64 |
5HT 10 um + epinephrine 10 μm | 264.6 (232.7, 296.5) | 241.5 (230.2, 252.9) | 0.14 |
5HT 10 μm + collagen 2μm | 253 (226.9, 279.2) | 238.7 (226.8, 250.7) | 0.37 |
5HT 10 μm + ADP 1μm | 229.7 (192.3, 267.2) | 216.2 (202.9, 229.5) | 0.46 |
5HT 10 μm | 11.5 (2.8, 20.3) | 4.5 (2.3, 6.0) | 0.007 |
| |||
Baseline Cardiovascular Hemodynamics
| |||
Females (n = 49) |
Males (n = 242) |
p Value | |
| |||
Baseline resting SBP | 128 (122.4, 132.9) | 127 (124.3, 128.9) | 0.73 |
Baseline resting DBP | 71 (68.0, 74.0) | 73 (71.6, 74.6) | 0.24 |
Baseline resting HR | 70 (66.7, 73.3) | 68 (66.2, 68.9) | 0.14 |
Baseline resting HR × SBP | 8,894 (8,313.5, 9,473.5) | 8,563 (8,323.2, 8,801.9) | 0.27 |
Values are % or mean (95% confidence intervals).
A nonparametric method of comparison was used.
ADP = adenosine diphosphate; BDI = Beck Depression Inventory; CESD = Center for Epidemiologic Studies Depression Scale; DBP = diastolic blood pressure; H/o = history of; HR = heart rate; SBP = systolic blood pressure; 5HT = serotonin.