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. 2015 Mar 4;1:14001. doi: 10.1038/npjschz.2014.1

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Copyright © 2015 Schizophrenia International Research Group/Nature Publishing Group

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Areas where changes in BOLD signal as a function of PE (PE-related BOLD signal) were significantly different in patients with schizophrenia compared with healthy controls (analyses restricted to ventral striatum/nucleus accumbens (left) and midbrain/SN (right) using small-volume correction; P<0.05). Clusters are overlaid on a single-subject T1 structural image. The numbers adjacent to the slices indicate y and z coordinates in Montreal Neurological Institute convention for coronal and axial slices, respectively. The color bar indicates t-values. BOLD, blood oxygen level dependent; PE, prediction error; SN, substantia nigra.