Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Mar 4;1:14001. doi: 10.1038/npjschz.2014.1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015 Schizophrenia International Research Group/Nature Publishing Group

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

Correlation between PE-related BOLD signal and SN Glx. (a) In healthy controls, but not in patients with schizophrenia, there was a significant correlation between PE-related BOLD signal and SN Glx in the SN (analyses restricted to ventral striatum and midbrain/SN using small-volume correction; P<0.05). Clusters are overlaid on a single-subject T1 structural image. The numbers adjacent to the slices indicate y and z coordinates in Montreal Neurological Institute convention for coronal and axial slices, respectively. BOLD, blood oxygen level dependent; Glx, glutamate+glutamine; PE, prediction error; SN, substantia nigra. (b) Scatterplots showing the distribution of variance in the relationship between Glx and PE BOLD response in healthy controls (r=0.74) and patients with schizophrenia (r=0.30).