Figure 6.

Typical planar bilayer conductance behavior for 7 and 9. (a) 7 (Aib₁₁, 0.6 μM), applied voltage −100 mV, current passed −150 pA; 1.5 nS. (b) 9 (Aib₁₃, 0.6 μM), applied voltage +100 mV, current passed +145 pA, with smaller conducting state also observed at +130 pA; 1.45 or 1.3 nS, respectively. (c) 9 (Aib₁₃), 0.6 μM concentration, applied voltage +100 mV, current passed +145 pA; 1.45 pS. (d) Example I–V traces: 9 (Aib₁₃, purple) and 7 (Aib₁₁, blue), traces approximately 1 h after addition of compound.