Table 1. Experimental NMR Dimerization Constants K (Dissociation Constants, Kd) for Foldamers 1, 2, 4, 7–9 in CDCl3 at 298 K.
oligomer | K/M–1 (Kd/mM) |
---|---|
Aib51 | <1 (>1000) |
Aib62 | 1.2 ± 0.2 (830 ± 140) |
Aib84 | 3.0 ± 1.3 (330 ± 140) |
Aib11 7 | 17.3 ± 3.1 (58 ± 10) |
Aib12 8 | 13.6 ± 0.6 (74 ± 3) |
Aib13 9 | 16.9 ± 0.4 (59 ± 1) |