Figure 1.

Overview of genetic aberrations identified in 28 patients with triple-negative ET or PMF. (A) Genetic findings from 4 of 8 studied patients, in which somatic genetic aberrations were identified using WES or microarray analysis. Somatic mutations are marked in black and germline mutations in blue. (B) Genomic overview of somatic mutations identified in 8 patients analyzed by WES and chromosomal aberrations found in 27 patients, detected with Affymetrix Genome-Wide Human SNP 6.0 microarrays. The position and size of the colored bars indicate the chromosomal aberrations. Red bars depict deletions, blue bars depict UPDs, and green bars depict gains.