Table 2. Summary of the characteristics of RSV cohort and comparison between those with positive and negative blood PCR for bacteria.
General data are presented as percentages or means with 95% confidence intervals. Different statistical models were used to assess the association between the variables: Fisher’s exact test (1) for discrete variables and Wilcoxon test (2) for continuous variables.
| Variables | Total cohort (n = 66) | Negative PCR (n = 59) | Positive PCR (n = 7) | P-value |
|---|---|---|---|---|
| Demographics | ||||
| Sex. Female1 | 33.3% (22/66) | 35.6% (21/59) | 14.3% (1/7) | 0.409 |
| Age (months)1 | 1.000 | |||
| < 12 | 92.4 (61/66) | 91.5 (54/59) | 100 (7/7) | |
| 12–24 | 3.0% (2/66) | 3.4% (2/59) | 0.0% (0/7) | |
| > 24 | 4.5% (3/66) | 5.1% (3/59) | 0.0% (0/7) | |
| Family history | ||||
| Asthma1 | 30.3% (20/66) | 71.2% (42/59) | 57.1% (4/7) | 0.425 |
| Respiratory conditions1 | 30.3% (20/66) | 28.8% (17/59) | 42.9% (3/7) | 0.425 |
| Medical history | ||||
| Premature1 | 4.8% (3/63) | 3.6% (2/56) | 14.3% (1/7) | 0.302 |
| Pneumococcal vaccine | 48.5 (32/66) | 52.5% (31/59) | 14.3% (1/7) | 0.106 |
| Clinical data | ||||
| Oxygen needed1 | 80.3% (53/66) | 78.0% (46/59) | 100.0% (7/7) | 0.329 |
| Any kind of respiratory support1 | 27.3% (18/66) | 18.6% (11/59) | 100.0% (7/7) | <0.001 |
| Diagnosis1 | 0.739 | |||
| Bronchiolitis | 78.8% (52/66) | 76.3% (45/59) | 100.0% (7/7) | |
| Pneumonia | 6.1% (4/66) | 6.8% (4/59) | 0.0% (0/7) | |
| Bronchial hyperreactivity | 15.2% (10/66) | 16.9% (10/59) | 0.0% (0/7) | |
| Respiratory distress1 | 0.001 | |||
| Mild | 22.7% (15/66) | 25.4% (15/59) | 0.0% (0/7) | |
| Moderate | 53.0% (35/66) | 57.6% (34/59) | 14.3% (1/7) | |
| Severe | 21.2% (14/66) | 13.6% (8/59) | 85.7% (6/7) | |
| PICU admission1 | 57.1% (28/49) | 50.0% (21/42) | 100.0% (7/7) | 0.015 |
| Fever1 | 0.733 | |||
| Low-grade fever (37–38°C) | 37.5% (18/48) | 36.6% (15/41) | 42.9% (3/7) | |
| Fever (> 38°C) | 50.0% (24/48) | 48.8% (20/41) | 57.1% (4/7) | |
| Wood Downes Score (mean-SD)2 | 5.2 (2.4) | 4.8 (2.2) | 8.7 (1.1) | <0.001 |
| GENVIP scale (mean-SD)2 | 11.1 (4.1) | 10.1 (3.6) | 17.0 (1.0) | <0.001 |
| Hospital length of stay (mean-SD)2 | 8.0 (4.8) | 7.5 (4.7) | 12.1 (4.3) | 0.007 |
| Suspected bacterial superinfection1 | 50.0% (33/66) | 45.8% (27/59) | 85.7% (6/7) | 0.105 |
| Blood culture | ||||
| Done. Yes1 | 60.0% (27/45) | 55.3% (21/38) | 85.7% (6/7) | 0.215 |
| Positive1 | 3.7% (1/27) | 0.0% (0/21) | 17.0% (1/6) | 0.222 |
1Fisher’s exact test.
2Wilcoxon test