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. 2016 Feb 12;11(2):e0149266. doi: 10.1371/journal.pone.0149266

Fig 7. Model mechanism for anti-fibrotic effects of Prdx5.

Fig 7

TGF-β mediates the progression of renal fibrosis through several signaling pathways. Overexpression of Prdx5 suppresses activation of Stat3, but has no effect on Smad2/3.