Table 2. Longitudinal relaxivity data (s-1mM-1) of Gd(ABE-DTTA) and Gd-DTPA obtained on NMRD, MRI and NMR instruments are shown along with the corresponding field strength (Tesla) and proton Larmor frequency (MHz).
Relaxivity (s-1mM-1) | |||||
---|---|---|---|---|---|
Equipment | Field (T) | Frequency (MHz) | Gd(ABE-DTTA) 0.5mM | Gd(ABE-DTTA) 1mM | Gd-DTPA 4mM |
NMRD | 0.0002 | 0.0099 | 23.51±0.21 | 28.25±0.05 | 6.54±0.17 |
0.0003 | 0.014 | 23.37±0.19 | 28.43±0.43 | 6.62±0.08 | |
0.0005 | 0.022 | 23.29±0.05 | 28.36±0.17 | 6.65±0.15 | |
0.0007 | 0.033 | 23.34±0.29 | 28.38±0.23 | 6.53±0.05 | |
0.0011 | 0.049 | 23.36±0.21 | 28.40±0.19 | 6.67±0.07 | |
0.0017 | 0.073 | 23.32±0.13 | 28.40±0.17 | 6.55±0.08 | |
0.0025 | 0.11 | 23.30±0.16 | 28.73±0.11 | 6.65±0.04 | |
0.0038 | 0.16 | 23.41±0.26 | 28.32±0.13 | 6.65±0.09 | |
0.0057 | 0.24 | 23.29±0.15 | 28.58±0.12 | 6.62±0.05 | |
0.0086 | 0.36 | 23.47±0.19 | 28.33±0.85 | 6.64±0.06 | |
0.012 | 0.54 | 23.54±0.32 | 28.44±0.21 | 6.67±0.07 | |
0.019 | 0.81 | 23.12±0.40 | 28.54±0.21 | 6.76±0.02 | |
0.028 | 1.21 | 23.15±0.28 | 28.33±0.30 | 6.77±0.14 | |
0.042 | 1.81 | 22.01±0.09 | 27.47±0.59 | 6.86±0.07 | |
0.063 | 2.7 | 20.67±0.12 | 26.44±0.26 | 6.85±0.18 | |
0.094 | 4 | 18.10±0.90 | 23.66±0.58 | 6.70±0.19 | |
0.14 | 6 | 15.63±0.03 | 21.37±0.05 | 6.51±0.12 | |
0.21 | 8.9 | 13.68±0.44 | 18.59±0.61 | 5.87±0.13 | |
0.31 | 13.4 | 12.48±1.11 | 16.76±0.34 | 4.91±0.07 | |
0.46 | 20 | 13.08±0.44 | 15.44±0.07 | 4.16±0.01 | |
0.58 | 25 | 13.32±0.13 | 15.27±0.13 | 4.02±0.02 | |
0.7 | 29.9 | 13.75±0.13 | 15.70±0.04 | 3.80±0.02 | |
0.93 | 40 | 14.22±0.09 | 16.20±0.07 | 3.80±0.01 | |
MRI | 1.5 | 64 | 15.33±0.37 | 18.10±0.16 | 3.60±0.14 |
3 | 128 | 11.87±0.04 | 16.67±0.10 | 3.34±0.05 | |
NMR | 7 | 300 | 12.46±0.08 | 13.51±0.04 | 3.04±0.00 |
9.4 | 400 | 11.87±0.04 | 13.28±0.66 | 2.94±0.03 | |
14 | 600 | 11.89±0.02 | 12.49±0.02 | 3.04±0.01 | |
16.4 | 700 | 11.63±0.27 | 12.48±0.02 | 3.10±0.03 | |
20 | 850 | 11.58±0.97 | 12.91±0.28 | 3.19±0.18 |