Table 3. Details for sequential dengue virus infections observed in the cohort.
| Study ID | |||||||
|---|---|---|---|---|---|---|---|
| Episode | 50877 | 50743 | 50730 | 51793 | 52159 | 52119 | |
| 1 | Date of illness | UNK | 24/10/2001 | UNK | UNK | UNK | UNK |
| Baseline sample date | 3/6/2002 | 31/7/2001 | 18/5/2001 | 30/10/2001 | 14/8/2001 | 10/4/2003 | |
| Acute sample date | N/A | 24/10/2001 | N/A | N/A | N/A | N/A | |
| Convalescent sample date | N/A | 8/11/2001 | N/A | N/A | N/A | N/A | |
| Serotype (method) | UNK | DENV-2(PCR,ISOL) | UNK | UNK | UNK | UNK | |
| IgM (acute/convalescent) | N/A | 3.4–8.9 | N/A | NA | N/A | N/A | |
| HI (acute/convalescent) | N/A | 10–640 | N/A | N/A | N/A | N/A | |
| PRNT 50% | DENV-4? | DENV-2 | DENV-1? | DENV-2 | DENV-2? | ? | |
| Baseline PRNT 50% (DENV-1,2,3,4) | <10,<10,10,17 | <10,<10,<10,<10 | 187,<10,12,<10 | <10,359,12,11 | 10,215,<10,<10 | <10,124,99,29 | |
| Acute PRNT 50% (DENV-1,2,3,4) | N/A | <10,84,<10,<10 | N/A | N/A | N/A | N/A | |
| Convalescent PRNT 50% (DENV-1,2,3,4) | N/A | 95,2556,15,18 | N/A | N/A | N/A | N/A | |
| Clinical Category | UNK | DF+HM | UNK | UNK | UNK | UNK | |
| 2 | Date of illness | 21/09/2002 | 02/08/2003 | 6/7/2001 | 5/1/2002 | 21/9/2001 | 6/6/2003 |
| Acute sample date | 21/09/2002 | 02/08/2003 | 6/7/2001 | 5/1/2002 | 21/9/2001 | 6/6/2003 | |
| Convalescent sample date | 7/10/2002 | 14/8/2003 | 17/7/2001 | 17/1/2002 | 1/10/2001 | 19/6/2003 | |
| Serotype (method) | DENV-1(PCR,ISOL) | DENV-3(PRNT) | UNK | DENV-3 (PCR) | DENV-4(PCR, ISOL) | DENV-4(PCR, ISOL) | |
| IgM (acute/convalescent) | 0.9–2.8 | 1.01–1.26 | 0.5–4.8 | 0.7–10.9 | 0.17–1 | 0.2–1.1 | |
| HI (acute/convalescent) | 10–5120 | 320–5120 | <10–640 | 160–10240 | <10–2560 | 10–2560 | |
| Acute PRNT 50% (DENV-1,2,3,4) | 383,234,328,35 | 243,1076,349,101 | <10,39,13,<10 | <10,165,10,<10 | <10,145<10,<10 | <10,133,<10,<10 | |
| Convalescent PRNT 50% (DENV-1,2,3,4) | 14205,87886,4374,162 | 343,19493,5900,154 | >25000,1463,6870,56 | 3402,>1000, 6042,490 | 139,3337, 301, 493 | 567,7404,1029,5414 | |
| Clinical Category | DF | DF+HM | DF | DF | DF | DHF gr II | |
| 3 | Date of illness | 4/4/2008 | N/A | 7/1/2002 | 14/7/2003 | 17/3/2003 | 25/5/2004 |
| Acute sample date | 4/4/2008 | N/A | 7/1/2002 | 14/7/2003 | 17/3/2003 | 25/5/2004 | |
| Convalescent sample date | 14/4/2008 | N/A | 17/1/2002 | 24/7/2003 | 27/3/2003 | 5/6/2004 | |
| Serotype (method) | DENV-3(PCR) | N/A | UNK | UNK | DENV-3(RT-PCR) | DENV-3(RT-PCR, ISOL) | |
| IgM (acute/convalescent) | 0.5–1.8 | N/A | 0.48–1.99 | 1.3–9.3 | 0.19–1.1 | 0.4–0.8 | |
| HI (acute/convalescent) | 80–10240 | N/A | 40–1280 | 160–2560 | 80–5120 | 80–5120 | |
| Acute PRNT 50% (DENV-1,2,3,4) | N/A | N/A | 809,76,127,18 | 77,764,172,137 | 51,505,57,61 | <10,345,<10,<10 | |
| Convalescent PRNT 50% (DENV-1,2,3,4) | N/A | N/A | 8124,5537,>1000,127 | >4500,16750,>1000,2126 | >6000,>1000,>6000,>4000 | 10720,>1000,12103,4146 | |
| Clinical Category | DF | N/A | DF | DF | DF | DF | |
UNK = unknown, ISOL = isolation, DF = dengue fever, HM = hemorrhagic manifestations, DHF = dengue hemorrhagic fever, DHF gr II = DHF grade II