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. 2016 Feb 12;11(2):e0149449. doi: 10.1371/journal.pone.0149449

Table 2. Percentage of patients receiving guideline-based care and mean number of fractions delivered.

Cancer Type Measure 2011 Fee-For-Service 2013 Case Rate RR 95% CI P-Value of Change in Mean
Bone mets.       2.0 (1.21–3.24)  
  % 30.2% 60.0%      
  n 43 75      
  Mean 13.7 11.4     0.03
  ±SD 5.5 5.6      
Breast       1.0 (0.94–1.04)  
  % 95.9% 95.1%§      
  n 123 143      
  Mean 29.7 30.4     0.31
  ±SD 5.1 6.0      
Lung       1.0 (0.89–1.09)  
  % 91.5% 91.5%      
  n 59 71      
  Mean 27.4 27.1     0.84
  ±SD 9.3 9.2      
Prostate       1.1 (1.01–1.15)  
  % 88.5% 95.2%      
  N 157 189      
  2D3D mean n/a n/a     n/a
  2D3D ±SD n/a n/a      
  2D3D n 0 0      
  IMRT mean 37.4 41.1     0.00
  IMRT ±SD 8.7 6.1      
  IMRT n 157 189      
Skin            
  % 100.0% 91.9% 0.9 (0.84–1.01)  
  n 51 37      
  2D3D mean 22.6 24.2     0.20
  2D3D ±SD 4.0 6.5      
  2D3D n 50 34      
  IMRT mean Redacted Redacted     Redacted
  IMRT ±SD Redacted Redacted      
  IMRT n 1 3      
Overall       1.0 (0.98–1.08)  
  % 86.6 89.3      
  n 433 515*      

Results redacted for groups with n<10.

CI = confidence interval, mets. = metastases, RR = relative risk, SD = standard deviation.

*An intent-to-treat approach was used for this population where case rates were introduced, yet not all patients were covered under the case rate arrangement. Results for 2D3D and IMRT fractionation are displayed separately for prostate and skin cancer due to the differences in the guidelines.

P < .05.

16–21 fractions were delivered to 8% of those who received guideline-based care (9/118).

§16–21 fractions were delivered to 10% of those who received guideline-based care (13/136).