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. 2016 Feb 12;11(2):e0148924. doi: 10.1371/journal.pone.0148924

Table 2. Mutations in HIV protease gene after previous virological failure (VF) on protease inhibitor-based regimen.

Protease mutations after previous VF on PI-based regimen (n = 158/205) n (%)
Wild type 59 (37.3)
Only mm (M, 2; range, 1–7) 48 (30.3)
1 MM (L90M, 25; D30N, 11; V82A, 2; N88S, 2; I50L/V, 2) + mm (M, 3; range, 0–8) 42 (26.6)
2 MM (V82A + L90M, 5; I84V + L90M, 2; N88S + L90M, 2; V82A + I84V, 1; D30N
+ N88S, 1; I54L + L90M, 1;) + mm (M, 6; range, 4–10) 12 (8.6)

PI, protease inhibitor. mm, protease minor mutations. MM, HIV protease major mutations; M, median. Specific major protease mutations in brackets.