Table 5. Functional clusters of genes with MCC > 0.6 with gene body probes selected by 1NN-SFS algorithm on the breast cancer cell line data.

Cluster Number	Number of genes	Enrichment	Most significant terms (p-val)	Other representative terms (p-val) and notes
1	48	2.84	Atp-binding (1.1E-51), Nucleotide-binding (6.5E-47), adenyl ribonucleotide binding (4.2E-45)	phosphorylation (4.8E-33), kinase (7.6E-40), transferase(1.9E-29)
2	12	2.36	Nucleolus (1.2E-14), nuclear lumen (3.9E-11), intracellular organelle lumen (3.7E-10)
3	11	2.06	Transcription regulation (1.6E-10), transcription(2.1E-10), regulation of transcription (6.8E-8)
4	9	1.83	Ribosomal protein (7.2E-17), ribonucleoprotein (1.8E-15), ribosome (5.6E-15)	RNA binding (2.8E-4)
8	6	1.39	Negative regulation of ubiquitin-protein ligase activity during mitotic cell cycles (2.2E-12), negative regulation of ubiquitin-ligaase activity (2.6E-12)	Genes coding for proteasomes and ubiquitin
9	66	1.38	Regulation of transcription (1.1E-34), transcription (2.4E-24), transcription regulation (5.0E-32)