Table 3. Summary of SNPs detection and the results of statistical analysis.
| Gene | Variant | Fisher test, P-value | Cochran-Armitage trend test, P-value | Logistic regression, OR, 95%CI | Power analysis |
|---|---|---|---|---|---|
| ABCB1 | rs3213619 | 0.340 | 0.184 | 0.27, 0.04–2.10 | 0.170 |
| ABCB1 | rs1128503 | 0.191 | 0.177 | 1.39, 0.86–2.25 | 0.264 |
| ABCB1 | rs1045642 | 0.803 | 0.817 | 1.06, 0.66–1.71 | 0.057 |
| CYP2C19 | rs12248560 | 0.472 | 0.559 | 1.96, 0.20–19.30 | 0.162 |
| CYP2C19 | rs4244285 | 0.787 | 0.813 | 1.06, 0.64–1.78 | 0.057 |
| CYP2C19 | rs4986893 | 1.000 | 0.760 | 0.82, 0.23–2.90 | 0.047 |
| CYP2C19 | rs3758580 | 0.175 | 0.180 | 1.60, 0.80–3.20 | 0.299 |
| CYP2C9 | rs4086116 | 0.130 | 0.149 | 1.59, 0.84–3.01 | 0.298 |
| CYP2C18 | rs2104543 | 0.172 | 0.159 | 1.42, 0.87–2.31 | 0.301 |
| CYP2C18 | rs12772169 | 0.136 | 0.124 | 1.46, 0.90–2.38 | 0.341 |
| CYP2C18 | rs1998591 | 0.270 | 0.261 | 1.32, 0.81–2.15 | 0.207 |
| CYP2C18 | rs1042194 | 0.694 | 0.719 | 1.10, 0.66–1.82 | 0.068 |
| PON1 | rs662 | 0.029* | 0.035* | 1.64, 1.03–2.62 | 0.517 |
| CES1 | rs1968753 | 0.900 | 0.877 | 1.04, 0.64–1.68 | 0.053 |
| CES1 | rs8192950 | 0.076 | 0.059 | 0.47, 0.21–1.04 | 0.493 |
| P2Y12 | rs2046934 | 0.041* | 0.021* | 2.01, 1.10–3.67 | 0.710 |
| P2Y12 | rs6798347 | 0.219 | 0.202 | 1.38, 0.84–2.27 | 0.248 |
| P2Y12 | rs6801273 | 0.212 | 0.188 | 0.71, 0.42–1.19 | 0.257 |
| P2Y12 | rs6787801 | 0.903 | 0.885 | 0.97, 0.60–1.55 | 0.051 |
| COX1 | rs1330344 | 0.017* | 0.014* | 1.85, 1.12–3.03 | 0.709 |
| COX1 | rs10306114 | 0.804 | 0.660 | 0.78, 0.26–2.36 | 0.057 |
| UCP2 | rs659366 | 0.083 | 0.073 | 0.64, 0.39–1.05 | 0.434 |
*P-value < 0.05