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. 2016 Feb 12;12(2):e1004495. doi: 10.1371/journal.pcbi.1004495

Table 1. Selected analogues* of ethylbenzene.

Name CAS No. Correlation Coefficient Rank* PBPK ref.
Ethylbenzene 100-41-4 1 [58]
Xylene 1330-20-7 0.999979 1 [58]
Toluene 108-88-3 0.999957 3 [58]
Benzene 71-43-2 0.999848 7 [58]
Dichloromethane 75-09-2 0.988299 54 [59]
Methyl iodide 21410-51-5 0.910114 283 [60]

*Chemical analogues were selected based on their similar published experimental designs (animal species = rats, route of administration = inhalation, time span = short term) relative to that of ethylbenzene-associated literature.

*The ranking of correlation coefficient among a total of 307 unique chemicals in the PBPK knowledgebase.